CarbonX: Engineered Carbon for Advanced Separations

Carbon X Delivers Selectivity

CarbonX sample extraction products are used worldwide by separation scientists to deliver unmatched purity, consistency and quality in their sample analysis. CarbonX family of carbon coated materials deliver consistent retention and capacity.

The adjacent illustration shows the common characteristics of both HPLC and sample prep media. CarbonX has both of these properties which makes it a more reproducible analytical material.

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CarbonX HPLC products deliver:

CarbonX Sample Preparation products deliver:

  • 5-10% carbon coatingvs 100% carbon thus allowing your problem compounds to elute and greater column lifetime.
  • Versatile pore size selection vs single size.
  • Selectivity for polar small molecule and therapeutic metabolites.
  • Selectivity for separations of geometric isomers.
  • Retention at high eluent temperatures.
  • Several types of CarbonX to choose from including COS and BOS.
  • Broad array of column dimensions.
  • Optimal selectivity for polar small molecule and therapeutic metabolites
  • Reduced matrix effects
  • Unsurpassed selectivity for polar compounds
  • Consistent retention and capacity, yielding the highest SPE recovery
  • Wide selection of sorbents
  • Broad array of formats

Selected Media

 

 

Selected Media

 

 

 

Sample Prep CarbonX Specifications

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HPLC and Guard CarbonX Specifications

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Sample Prep, HPLC, Preparative CarbonX Chemistries

CarbonX Sorbents are available in 10 different solid-phase extraction (SPE) chemistries, providing a range of options for method development.

Structure

Application

Description

HPLCPrepSample PrepGuardTrap

CarbonX COS

Water-wettable. Chemical structure of carbon covering the surface of a porous silica particle. Non endcapped. Exposed silanols. pKa ~ 5. pH Stable from 0-14 under typical SPE elution conditions.

Particle Diameter: 30-60 micron Pore Diameter: 60 Angstroms Max Pressure: 5000 psi

HPLC Particle: see specifications tab.

Extraction of acid, bases, and neutrals from aqueous or organic matrix using polarphilic, hydrophobic, and hydrogen bond interactions.

PrepSample PrepGuardTrap

CarbonX Plus

Water-wettable. Chemical structure of carbon covering the surface of a proprietary particle. Surface contains alumina endcapped with phosphate ion. pH Stable from 0-14 under typical SPE elution conditions.

Particle Diameter: 30-60 micron Pore Diameter: 60 Angstroms Max Pressure: 5000 psi

Pigment removal material. Extraction of acid, bases, and neutrals from aqueous or organic matrix using polarphilic, hydrophobic, and hydrogen bond interactions.

PrepSample PrepGuardTrap

CarbonX COF

Water-wettable. Chemical structure of carbon covering the surface of a porous magnesium silicate particle. Non endcapped. Exposed silanols. pKa ~ 5. pH Stable from 0-14 under typical SPE elution conditions.

Particle Diameter: 30-60 micron Pore Diameter: 80 Angstroms Max Pressure: 5000 psi

Extraction of polar acid, bases, and neutrals from aqueous or organic matrix using polarphilic, hydrophobic, and hydrogen bond interactions. Useful for halogenated polar compounds.

HPLCPrepSample PrepGuard

CarbonX BOS

Water-wettable. Chemical structure of bonded mixed mode fullerene on a porous silica particle. pH Stable from 0-14 under typical SPE elution conditions.

Particle Diameter: 30-60 micron Pore Diameter: 80 Angstroms Max Pressure: 5000 psi

HPLC Particle: see specifications tab.

Extraction of polar acid, bases, and neutrals from aqueous or organic matrix using anion exchange, polarphilic, hydrophobic, and hydrogen bond interactions. Less retentive than COS, COA.

 

PrepSample PrepGuard

CarbonX COA

Water-wettable. Chemical structure of carbon covering the surface of a porous alumina particle. Surface contains alumina endcapped with phosphate ion. pH Stable from 0-14 under typical SPE elution conditions.

Particle Diameter: 30-60 micron Pore Diameter: 60 Angstroms Max Pressure: 5000 psi

Extraction of acid, bases, and neutrals from aqueous or organic matrix using Lewis Acid, polarphilic, hydrophobic, and hydrogen bond interactions. Highly mixed mode.

 

 

CarbonX products come in a full range of device formats to meet your SPE and HPLC requirements.

96-Well Extraction Plates

  • Standard Axygen 96 well plates
  • High throughput and high recovery
  • Available in 5 mg, 10 mg, 30 mg, and 60 mg per well
  • Compatible with most liquid-handling robotic systems for automated, reliable high throughput SPE (HT-SPE)

SPE Cartridges

  •  Ultra-clean syringe barrel and frits
  • Available in cartridges ranging from 1 cc to 60 cc
  • Also available in 150 mL cartridges with Luer inlet hub and outlet tip with 150 mg sorbent

FEP Cartridges

  • Ultra-clean glass syringe with Teflon® frit
  • For trace level detection and analysis at part-per-trillion (PPT) levels
  • Available in 5 cc (200 mg) configuration

On-Line Columns and Cartridges

  • For rugged, reproducible, and ultra-fast on-line analysis
  • Wide choice of configurations, particle sizes, and sorbent chemistries
  • Available with CarbonX and CarbonX PLB sorbents—COA, COA, BOS, COF, PLB, PCX, PAX, PCX, and PWAX
  • High recovery and reproducible results for a wide range of compounds.

HPLC Columns

  • Ideal for retenion of polar molecules in reverse or normal phase.
  • Selective for geometric isomers.

Elution Spin Columns

  • No evaporation and reconstitution necessary due to elution volumes as low as 25 µL
  • Ideal for SPE cleanup and analyte enrichment of small sample volumes
  • Up to a 15x increase in concentration
  • Compatible with most liquid-handling robotic systems for automated, reliable high throughput SPE (HT-SPE)

Dual and Tri Phase SPE Cartridges

  • Configure your SPE with up to 3 sorbents
  • Ultra-clean syringe barrel and frits
  • Available in cartridges ranging from 1 cc to 60 cc
  • Also available in 150 mL cartridges with Luer inlet hub and outlet tip with 150 mg sorbent

 

Method Development Kits for Sample Preparation

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On Line Trap Columns

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